Search Results - neurosciences

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Staircase Method for Optimized Therapeutic Hypothermia
Tech ID: lyd000931IntroductionTherapeutic hypothermia is used in patients suffering stroke, cardiac arrest, head trauma, subarachnoid hemorrhage, and in infants after hypoxic-ischemic injury. In several clinical trials published to date, therapeutic hypothermia has failed to show benefits commensurate with the benefit predicted from animal studies....
Published: 7/19/2018   |   Inventor(s): Patrick Lyden, Padmesh Rajput, Konrad Schlick, Mani Nezhad, Jessica Lamb
Keywords(s): Neurosciences
Category(s): Therapeutics/prophylactic, Device(s)
Adrenoceptors Antagonists for the Prevention and Treatment of Neurodegenerative Conditions
Tech ID: tag000709IntroductionThis invention discloses a new strategy to treat Idiopathic Parkinson’s Disease (iPD) at the stage that precedes the motor symptom state, known as “pre-motor symptom” stage, using adrenoceptor antagonists such as β-blockers. Also included is a non-invasive method to diagnose iPD and monitor its p...
Published: 3/30/2018   |   Inventor(s): Michele Tagliati, Gennaro Pagano
Keywords(s): Neurosciences
Category(s): Therapeutics/prophylactic
Device for Advanced Functional Brain Monitoring With and Without Simultaneous Brain Fluid Drainage - Ventrode
Tech ID: ros000984IntroductionPlacing an external ventricular drain is commonly the first, life-saving procedure performed on many patients with moderate to severe brain injury or an obstruction of brain fluid. Furthermore, surface electroencephalography (EEG), which uses electrodes placed on a patient’s scalp, is used to monitor electrical s...
Published: 3/19/2018   |   Inventor(s): Axel Rosengart, Ueli Rutishauser
Keywords(s): Neurosciences
Category(s): Device(s)
Detection and Quantification of Brain Motion and Pulsatility - BrainPulse
Tech ID: ros000989IntroductionThe cyclic perfusion of the brain with arterial blood induces “brain pulsations,” which are predictable expansions and relaxations of the brain. Brain injury leads to tissue density changes (“swelling” or “congestion”) of various degrees depending on injury location and the extent of...
Published: 12/6/2016   |   Inventor(s): Axel Rosengart
Keywords(s): Neurosciences
Category(s): Device(s)
Using Dual GLP-1/GIP Receptor Agonists to Treat Brain Insulin Resistance, Mild Cognitive Impairment and Alzheimer’s Disease Dementia
Tech ID: tal000941IntroductionAlzheimer’s disease (AD) poses one of the great challenges to 21st century medicine. It is the 6th leading cause of death in the US and after more than a century since its discovery, there are still no clinically effective treatments for AD that substantially slow or stop its progression. If the current situation...
Published: 8/4/2016   |   Inventor(s): Konrad Talbot, HoaU-Yan Wang, Keith Black
Keywords(s): Neurosciences
Category(s): Therapeutics/prophylactic
Apo A-1 Milano for Alzheimer's Disease
Tech ID: sha482/059/470/400IntroductionApolipoprotein A-I (ApoA-I) is the major structural protein component of high-density lipoprotein (HDL). Apolipoprotein A-I Milano (ApoA-IM), a naturally occurring Arg173 to Cys mutant of ApoA-I, was found in a small number of inhabitants of a northern Italian town. Compared to the normal gene (apolipoprotein ...
Published: 12/21/2015   |   Inventor(s): Prediman Shah
Keywords(s): Gene Therapy, Neurosciences
Category(s): Therapeutics/prophylactic