Left Atrial Appendage Occlusion Device

Tech ID: sie000664



The left atrium of the heart has a connected pouch-like structure called the left atrial appendage (LAA). Blood flows between the left atrium and the LAA during the normal operation of the heart. During atrial fibrillation, a common cardiac arrhythmia, the irregular beating of the heart can result in some stagnant blood in the LAA. This lack of blood flow can lead to the formation of blood clots that travel out of the heart and into the body causing stroke, heart failure, and other complications. LAA occlusion is one method to reduce strokes by closing the pouch where the blood pools.



Dr. Robert Siegel from the Cedars-Sinai Medical Center has developed a device that reduces the risk of deadly strokes in patients by closing the opening of the LAA and preventing blood pooling. It consists of a low-profile catheter that positions a balloon-like structure into the opening of the LAA to block it. The device prevents clots from traveling out of the heart and into the body. The device allows at-risk patients to be free from taking blood-thinning medications to prevent these blood clots.


Stage of Development

Concept only



Low profile catheter design makes for an easier to use LAA occlusion device as compared to current solutions.



LAA occlusion


Intellectual Property

• PCT application filed - PCT/US2014/039438

o Nationalized in Europe and the U.S.

Patent Information:
For Information, Contact:
Julien Brohan
Robert Siegel
Matthew Price
Nina Wunderlich