Device for Advanced Functional Brain Monitoring With and Without Simultaneous Brain Fluid Drainage - Ventrode

Tech ID: ros000984

 

Introduction

Placing an external ventricular drain is often the first life-saving procedure indicated in many patients with moderate to severe brain injury or obstruction of brain fluid of various types.  Surface electroencephalography (EEG) is then used to monitor patients with brain injury who are at a higher risk for seizure and to understand the injured brain’s general neuronal activity and evaluate recovery potentials. This is done by placing multiple electrode pads on the scalp and obtaining brain electrical waves.  However, EEG is not a very sensitive method to obtain brain electrical activities.

 

No device exists that allows combined CSF drainage and electrical seizure or cortical neuron activity monitoring in brain-injured patients.

 

Technology Description

Dr. Rosengart from Cedars-Sinai Medical center conceived a device that combines a multichannel electrode with a drainage conduit.

 

While being capable of draining cerebrospinal fluid, the device simultaneously enables monitoring of:

• Cortical brain electrical activity with single neuronal recordings.

• Deep brain electrical activity throughout the brain parenchyma to detect seizures at a network level.

 

Stage of Development

Concept

 

Advantages/Novelty

Such combination does not currently exist and brain-injured patients would benefit from the ability to monitor intracranial electrical activity while simultaneously obtaining CSF drainage and pressure.

Cortical single neuron recordings have not been established in the acute care setting and would provide very unique prognostic and treatment parameters.

 

Applications

The disclosed device will provide additional diagnostic, prognostic, and other useful information helpful to manage the care of acutely brain-injured patients.

 

Intellectual Property

• US provisional patent application filed.

 

Patent Information:
Category(s):
Device(s)
For Information, Contact:
Julien Brohan
julien.brohan@cshs.org
Inventors:
Axel Rosengart
Ueli Rutishauser
Keywords:
Neurosciences