Detection and Quantification of Brain Motion and Pulsatility - BrainPulse

Tech ID: ros000989

 

Introduction

The cyclic perfusion of the brain with arterial blood induces reflective movements of the brain tissue leading to predictable expansion and relaxation of the brain which can be termed ‘brain pulsations.’

Brain injury leads to tissue density changes (‘swelling or congestion’) affecting the brain to various degrees depending on the injury location and extent. As a result of the swelling, the arterial blood flow-induced cyclic brain pulsations become abnormal. Detecting abnormalities of brain pulsations by employing a non-invasive and easily applicable method for brain injury diagnosis and monitoring is of great clinical interest.

 

Technology Description

Dr. Rosengart from the Cedars-Sinai Medical Center has invented an ultrasound-based device to diagnose and monitor brain injury through the measurement of brain pulsatility.

This method involves the monitoring and quantification of brain movements and arterial pulse waveform by employing ultrasound transducers placed on the head and neck as well as comparing the expected versus obtained brain pulsatility measurements.

 

Stage of Development

Concept only

 

Advantages/Novelty

This method is non-invasive when compared to external ventricular drainage used to obtain cerebrospinal fluid pulsation and pressure.

This method offers a non-cumbersome and portable way to obtain real-time brain injury diagnostics when compared with Magnetic Resonance Imaging of the brain used to detect brain and CSF motion, which only offers a brief snapshot.

 

Applications

Diagnostic and monitoring of brain injury

 

Intellectual Property

• US provisional patent application filed.

Patent Information:
Category(s):
Device(s)
For Information, Contact:
Julien Brohan
julien.brohan@cshs.org
Inventors:
Axel Rosengart
Keywords:
Neurosciences