Device for Advanced Functional Brain Monitoring With and Without Simultaneous Brain Fluid Drainage - Ventrode

Tech ID: ros000984

 

Introduction

Placing an external ventricular drain is commonly the first, life-saving procedure performed on many patients with moderate to severe brain injury or an obstruction of brain fluid. Furthermore, surface electroencephalography (EEG), which uses electrodes placed on a patient’s scalp, is used to monitor electrical signals of a patient who is at higher risk for seizures and to understand the injured brain’s general neuronal activity and recovery potentials. However, a surface EEG is not a very sensitive method to obtain brain electrical activities. No device exists that allows for simultaneous CSF drainage and accurate electrical seizure or cortical neuron activity monitoring in patients with brain injuries.

  

Technology Description

Dr. Axel Rosengart from the Cedars-Sinai Medical Center has developed a catheter-type ventrode that combines a multichannel electrode with a drainage conduit. The device is inserted into a patient’s skull and enables brain fluid drainage while monitoring:

• Cortical brain electrical activity with single neuronal recordings

• Deep brain electrical activity throughout the brain parenchyma to detect seizures at a network level

 

Stage of Development

Concept

 

Advantages/Novelty

• Such combination does not currently exist and brain-injured patients would benefit from the ability to monitor intracranial electrical activity while simultaneously obtaining CSF drainage and pressure.

• Cortical single neuron recordings have not been established in the acute care setting and would provide very unique prognostic and treatment parameters.

 

Applications

The disclosed device will provide additional diagnostic, prognostic, and other useful information helpful to manage the care of acutely brain-injured patients.

 

Intellectual Property

• PCT Application filed - PCT/US2017/046329

Patent Information:
Category(s):
Device(s)
For Information, Contact:
Julien Brohan
julien.brohan@cshs.org
Inventors:
Axel Rosengart
Ueli Rutishauser
Keywords:
Neurosciences